Biotin

History

• Biotin is the name given to a substance isolated from egg yolk in 1936 (necessary for yeast growth)

Function

• A coenzyme in energy reactions requiring fixation of CO2 to various compounds

Structure

• A sulfur-containing vitamin

• The coenzyme form is biocytin:

Biotin with CO2 bound to the enzyme at the amino group of a lysine residue (apoenzyme)

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